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ROS levels have been reported to be increased in oesophagitis compared to healthy controls in both patients and murine models and are hypothesized to mediate mucosal damage and drive disease progression.44, 45 Administration of many antioxidants have been shown to prevent mucosal damage in models of oesophagitis suggesting that antioxidant treatment should be considered as a therapy in the treatment of oesophagitis.33, 45 Alternative treatments are commonly used for various disorders and are often taken on‐demand

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Its multifaceted mechanism of action, targeting both central and peripheral pathways involved in glucose and energy homeostasis, positions it as a promising agent in the evolving landscape of metabolic and neurodegenerative disease management

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