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Unfortunately, there is not adequate research at this time to help us understand how taking hormones as part of a gender-affirming process may impact an individual’s experience of alcohol’s effects
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In combination with bupropion, naltrexone, a µ-opioid receptor antagonist, acts in a synergistic manner to stimulate weight loss by blocking the β-endorphin-mediated inhibition of the POMC neuron [192]
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