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An iron-containing outer mitochondrial membrane protein, CDGSH iron sulfur domain 1 (CISD1), negatively regulates ferroptotic HepG2 death by protecting against mitochondrial lipid peroxidation (Yuan et al., 2016)
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Assays performed with leaf extracts of these lines indicated that GSAAT(C138S) and GSAAT(C396) are weakly stimulated by the addition of DTT (by up to 20% compared to their UT samples)
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