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Abbreviations Akt protein kinase B BDNF brain-derived neurotrophic factor ERK extracellular signal-regulated kinases GCL glutamate cysteine ligase GSH glutathione GPCR G-protein coupled receptors Keap1 Kelch-like ECH-associated protein JNK Jun N-terminal kinases MAPKs mitogen activated kinases MOR mu-opioid receptor MT metallothionein NMDA N-methyl-D-aspartate NMDAR N-methyl-D-aspartate receptor NO nitric oxide Nrf2 transcription factor NF-E2-related factor 2 PKC protein kinase C PTPs protein tyrosine phosphatases RXR retinoid X receptor VDR 1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)) receptor Footnotes Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication