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The in vivo relevance of necroptosis, NETs, and the alternative complement pathway, specifically the C5a-C5a receptor interaction, for disease induction was established in murine MPO-AAV models (135, 153–155)
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3.5.5 Isothiocyanates emerge as potent miRNA modulators across cancer types Sulforaphane demonstrates extensive miRNA effects with well-characterized targets across multiple cancer types
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