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During acute COVID-19, circulating concentrations of these cytokines increase substantially, particularly in severe disease, creating conditions that may disrupt normal HPO axis signaling and activate the hypothalamic-pituitary-adrenal (HPA) axis, resulting in increased cortisol secretion
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DHHB (Dihydrohonokiol-B) is an oral supplement derived from magnolia bark with neuroprotective and anxiolytic properties
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