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People take vitamin B12 supplements for various reasons, including: To compensate for an existing deficiency or insufficiency During pregnancy Because they have a genetic variation that impairs B12 absorption from foods For energy Because they are taking certain medications that impair their ability to absorb B12 Because they have gut health issues and suspect or have confirmed they are not absorbing enough vitamin B12 To improve mental/emotional well-being For hair, skin, or nail health Because they are vegan or vegetarian and may not get enough Vitamin B12 from food