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The Myc oncoprotein directly stimulates glutamine uptake by binding to promoters of glutamine metabolism genes (e.g., the glutamine transporter SLC1A5) and indirectly enhances glutaminolysis by repressing microRNA miR-23a/b, a negative regulator of GLS1 (36, 88)
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Treatment can also be done empirically and often starts with quercetin 30 min prior to meals alongside DAO, mirica, antihistamines In summary, the treatment of mold and mycotoxin associated illness is complex and the patients are generally quite sensitive to treatment as well
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