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The Wake Forest University School of Medicine Alzheimer’s Disease Research Center is coordinating the study, which is sponsored by the Alzheimer’s Drug Discovery Foundation (ADDF)

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For NAD + boosters to be used widely as drugs, it will be important to know their safety profile and understand fundamental aspects of NAD + biology and physiology, such as the tissue distribution of NAD + precursors and other NAD boosters, their transport into the cell and into organelles, and the metabolism of NAD + intermediates in the gut, the bloodstream, on the plasma membrane, and within organelles