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Manipulating CSE and ETHE1 levels in both directions, we found a consistent pattern in that the two enzymes mirrored each other: silencing CSE yielded the same effect (slower radical removal) as overexpressing ETHE1, and overexpressing CSE yielded the same effect (faster radical removal) as silencing ETHE1 (Fig
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Ferritin improves cognition by decreasing ROS and glutathione depletion in the MCAO model and downregulating elevated ferroptosis factors P11 and SLC53A7 ( 8 Ferroptosis affects atherosclerosis and depression through different mechanisms We have summarized the key mechanisms of cellular ferroptosis in AS and depression
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