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6.3 Limitations of novel delivery systems Although recent studies have reported substantial improvements in the delivery efficiency and therapeutic performance of flavonoids using advanced delivery systems, including enhanced stability, bioavailability, and targeting efficiency (Delgado-Pujol et al., 2025), several practical and clinical limitations have been identified, which merit further investigation and refinement
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Second, as I discussed with Santhosshi Narayanan, M.D., in a recent Cancerwise podcast episode, supplements aren’t regulated by the Food and Drug Administration (FDA)
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