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NRF2 editing affected the ability of SF to induce genes involved in Glutathione Metabolism (NES WT 1.8, q=0.008 vs 1.1 NRF2 KD, q=0.57), Metabolism of Xenobiotics by Cytochrome P450 (NES WT 1.83, q=0.006 vs 1.2 NRF2-KD, q=0.53) and PPP (NES WT 1.73, q=0.004 vs 0.72 NRF2-KD, q=0.91) (Table 3, Fig