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Effect of CAR and VAL on hippocampal levels of PI3K and mTOR in PTZ-induced kindling model PTZ-induced kindling markedly activated the hippocampal PI3K/mTOR pathway, as reflected by significant increases in both PI3K and mTOR levels by approximately 3.5-fold and 3.8-fold, respectively, compared with the CTRL group
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8C), the VPA-ASD model was associated with an overgrowth of Clostridium and a near-absence of beneficial genera like Akkermansia and Lachnospiraceae_NK4A136_group
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