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As exhibited in a prior study, increased MAM formation elevated cytoplasmic Ca 2+ levels, which promoted the phosphorylation of serum response factor (SRF) and its binding to the vascular endothelial growth factor receptor 2 (VEGFR2) promoter, producing VEGFR2 and thereby promoting inflammatory angiogenesis

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Alkaloids Alkaloids, organic compounds containing nitrogen, are found in plants, fungi, and bacteria and include well-known analgesic compounds such as tetrahydropalmatine, matrine, and tetrandrine [93,94]