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An important role of GSSG in the NFkappaB activating signal cascade is suggested by the facts that the potent NFkB inducer, tetradecanoyl phorbol acetate, increases intracellular GSSG levels and GSSG/GSH ratios

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Then, the samples were processed using modified filter-aided sample preparation (FASP) method ( 2.2 Experimental animals and design Male and female ICR-CD1 mice aged between 4–6 weeks and 25–35 g, obtained from the Centre for Comparative Medicine Research (CCMR) of the University of Hong Kong, were used in the study