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doi: 10.1016/j.neuron.2016.06.033, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 22

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It is the combined characteristics of both membranes that determine which molecules traverse the BBB and how fast ( slc2a 1(glucose), slc16a1 (lactate, pyruvate), slc7a1 (cationic amino acids), and slc7a5 (neutral amino acids, L-DOPA) ( Amino Acid Transporters The concentration of AAs in brain extracellular fluid and cerebral spinal fluid is at least tenfold lower than plasma concentrations