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Phase I and II enzymes are present in high amounts in hepatocytes that process circulating phytochemicals and drugs, but are also expressed in cells of organ systems that are more directly exposed to the chemicals including the gut, lungs, and skin (Zhang et al., 2006
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To elute hercynine and S-methyl ET, solvent B was increased to 90% in 1 min, and maintained for 3.5 min before returning to 20% for 3.5 min to re-equilibrate the column
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